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Clin Implant Dent Relat Res. 2019 Mar;21 Suppl 1:55-68. doi: 10.1111/cid.12749. Epub 2019 Mar 12.

A randomized, controlled, clinical study on a new titanium oxide abutment surface for improved healing and soft tissue health.

Author information

1
The Brånemark Clinic, Public Dental Health Service, Västra Götaland, Gothenburg, Sweden.
2
Faculty of Odontology, Malmö University, Malmö, Sweden.
3
Department of Oral and Maxillofacial Radiology, Institute of Odontology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

Abstract

BACKGROUND:

A newly developed, anodized titanium oxide surface containing anatase has been reported to have antimicrobial properties that could reduce bacterial adherence to abutments.

PURPOSE:

To investigate if abutments with the anodized surface improve healing and soft tissue health in a randomized controlled study.

MATERIALS AND METHODS:

Test abutments with a nanostructured anodized surface were compared with control machined titanium abutments. In total, 35 subjects each received a pair of test and control abutments. The primary endpoint was reduction of biofilm formation at test abutments at the 6-week follow-up. Secondary endpoints included several soft tissue assessments. qPCR for gene markers was used to indirectly evaluate healing and soft tissue health.

RESULTS:

No significant differences in biofilm formation were observed between test and control abutments, but soft tissue bleeding upon abutment removal was significantly lower for test abutments compared with control abutments (P = 0.006) at 6 weeks. Keratinized mucosa height was significantly greater at test abutments compared with control abutments at the 6-week, 6-month, and 2-year follow-ups. Significant gene expression differences indicated differences in healing and tissue remodeling.

CONCLUSIONS:

Abutments with an anodized and nanostructured surface compared with a conventional, machined titanium surface had no significant effect on bacterial colonization and proteolytic activity but were associated with better soft tissue outcomes such as a lower bleeding index at abutment removal and consistently greater height of keratinized mucosa throughout the 2-year follow-up, suggesting improved surface-dependent peri-implant healing and soft tissue health.

KEYWORDS:

RCT; bleeding on probing; keratinized mucosa height; new abutment surface; soft tissue healing and health

PMID:
30859691
DOI:
10.1111/cid.12749

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