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Orthop Clin North Am. 2019 Apr;50(2):171-179. doi: 10.1016/j.ocl.2018.12.001.

Vitamin D and Metabolic Supplementation in Orthopedic Trauma.

Author information

1
Department of Orthopaedics, Orlando Health, Orlando Health Orthopaedic Institute, 1222 South Orange Avenue, MP 43, Orlando, FL 32806, USA.
2
Level One Orthopedics, Orlando Health, Orlando Health Orthopaedic Institute, 1222 South Orange Avenue, MP 43, Orlando, FL 32806, USA. Electronic address: favilucea@gmail.com.

Abstract

Active assessment and management of hypovitaminosis D among orthopedic patients is low-risk and low-cost while retaining significant potential to improve patient care. Vitamin D has an established role in musculoskeletal development and calcium homeostasis, and vitamin D deficiency is pervasive in orthopedic trauma populations. Clinical guidelines for screening and supplementation for hypovitaminosis D are lacking. Literature on the effects of vitamin K on bone health is limited. Anabolic hormone analogues may have a future role in delayed union or nonunion treatment. Vitamin D deficiency and other endocrine abnormalities should be considered in orthopedic trauma patients presenting with fracture nonunion of uncertain cause.

KEYWORDS:

Endocrine; Fracture healing; Fracture nonunion; Hypovitaminosis D; Metabolic; Vitamin D; Vitamin D supplementation

PMID:
30850076
DOI:
10.1016/j.ocl.2018.12.001
[Indexed for MEDLINE]

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