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Heart. 2019 Mar;105(Suppl 2):s21-s27. doi: 10.1136/heartjnl-2018-313514.

Patient-specific computer simulation for transcatheter cardiac interventions: what a clinician needs to know.

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Department of Cardiology, Thoraxcenter, Erasmus MC, Rotterdam, The Netherlands.
IBiTech-bioMMeda, Ghent University, Ghent, Belgium.
Department of Cardiology, Guy's and St Thomas' NHS Foundation Trust London, London, UK.
Department of Cardiology, Rigshospitalet University Hospital, Copenhagen, Denmark.


Patient-specific computer simulation consists of the assessment of the interaction of the device with the host based on the integration of the detailed geometric and biomechanical properties of the device and host. Hence, it allows the prediction of valve performance (efficacy) and complications (safety) and may consequently help the physician to select the valve/device that best fits the individual patient, thereby improving outcome. There is currently little awareness and information in clinical medicine on patient-specific computer simulation. In this paper, we describe the technical background and a number of illustrations to illustrate how patient-specific computer simulation may be used for catheter-based treatment planning of acquired heart disease.


aortic stenosis; mitral regurgitation; transcatheter valve interventions

Conflict of interest statement

Competing interests: GR is an engineer and employee of Feops, Ghent, Belgium.

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