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Am J Emerg Med. 2019 Feb 22. pii: S0735-6757(19)30113-5. doi: 10.1016/j.ajem.2019.02.029. [Epub ahead of print]

Clinical spectrum of previously undiagnosed pediatric cardiac disease.

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UNLV School of Medicine, Department of Emergency Medicine, United States of America. Electronic address:
UNLV School of Medicine, Department of Emergency Medicine, United States of America.


Previously undiagnosed pediatric cardiac disease represents a clinical challenge for the emergency physician. The clinical presentation of these disorders can mimic other conditions of the respiratory, gastrointestinal and neurologic systems at a time when the need for early identification and treatment is at a premium. A high index of suspicion and superb clinical acumen is required to make a timely diagnosis and initiate optimal care.


A retrospective chart review using explicit criteria and a structured data collection process was performed on all children presenting with previously undiagnosed cardiac disease over a five and half year period.


Thirty-six patients were identified over a five and a half year period representing one patient per 4838 pediatric ED presentations. A diverse set of chief complaints, triage categories, clinical presentations and diagnoses were identified. Undiagnosed congenital lesions, acquired cardiac disease, dysrhythmias and infectious diseases of the heart were represented. The need for surgical intervention (22%) and mortality (6%) was substantial.


In the aggregate, these conditions occur at an important rate and represent a high risk subset of pediatric patients presenting to the emergency department. Individually, the conditions occur infrequently and 'pattern recognition' may not aid the clinician. Early diagnosis and prompt intervention is important in this population.


Arrhythmia; Cardiology; Congenital; Myocarditis; Pediatrics; Triage


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