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Int J Infect Dis. 2019 Mar;80S:S6-S8. doi: 10.1016/j.ijid.2019.02.036. Epub 2019 Feb 26.

A Breath of Fresh Air: BCG Prevents Adult Pulmonary Tuberculosis.

Author information

1
Infectious Disease and International Health, Geisel School of Medicine at Dartmouth, Hanover, NH, USA.
2
Infectious Disease and International Health, Geisel School of Medicine at Dartmouth, Hanover, NH, USA. Electronic address: C.Fordham.von.Reyn@dartmouth.edu.

Abstract

OBJECTIVES:

The efficacy of childhood BCG vaccination in the prevention of adult pulmonary tuberculosis is not universally accepted.

METHODS:

We reviewed the published literature and summarized studies of BCG vaccination reporting long-term protection against pulmonary TB.

RESULTS:

We identified 15 papers reporting prospective studies and their long-term follow up, retrospective studies or systematic reviews.

CONCLUSIONS:

Good quality evidence supports the efficacy of BCG vaccination in the prevention of adult pulmonary tuberculosis.

KEYWORDS:

BCG; tuberculosis; vaccine

PMID:
30822546
DOI:
10.1016/j.ijid.2019.02.036
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