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J Alzheimers Dis. 2019;68(2):523-529. doi: 10.3233/JAD-181080.

Patient Perceptions of Antihypertensive Use as a Dementia Prevention Strategy: A Mixed-Method Analysis of a Web-Based Survey.

Author information

1
University of Washington, School of Pharmacy, Seattle, WA, USA.
2
University of Washington, School of Public Health, Seattle, WA, USA.
3
University of Washington, School of Medicine, Seattle, WA, USA.
4
Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA.

Abstract

We administered a mixed-method survey to 1,661 patients in a large health system to assess preferences toward antihypertensive use for dementia prevention. If a specific antihypertensive medication was shown to prevent or delay dementia, the vast majority (>90%) of respondents currently taking an antihypertensive reported that they would be willing to take that specific antihypertensive starting as early as mid-life. Concerns reported were potential side effects, lack of evidence of effectiveness, blood pressure being normal or low, and medication cost. Analysis of free-text responses revealed themes of concerns regarding evidence of effectiveness and health priorities.

KEYWORDS:

Alzheimer’s disease; antihypertensive agents; dementia; primary prevention

PMID:
30814348
DOI:
10.3233/JAD-181080

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