Format

Send to

Choose Destination
Sci Rep. 2019 Feb 26;9(1):2746. doi: 10.1038/s41598-019-38928-6.

Early differentiation of long-standing persistent atrial fibrillation using the characteristics of fibrillatory waves in surface ECG multi-leads.

Author information

1
Department of Cardiology, College of Medicine, Ewha Womans University, Seoul, South Korea.
2
Cardiovascular Devices Division, National Institute of Food and drug safety Evaluation, Cheongju-si, South Korea.
3
Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, United States.
4
Department of Cardiology, Medical College of Wisconsin, Milwaukee, WI, USA.
5
Department of Internal Medicine, College of Medicine, Yonsei University, Seoul, South Korea.
6
Division of Cardiology, Kyung Hee University Medical College, Seoul, South Korea.
7
Division of Cardiology, Yonsei University Health System, Seoul, South Korea.
8
Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, United States. hhwang@bidmc.harvard.edu.

Abstract

We characterized the f-waves in atrial fibrillation (AF) in the surface ECG by quantifying the amplitude, irregularity, and dominant rate of the f-waves in leads II, aVL, and V1, and investigated whether those parameters of the f-waves could discriminate long-standing persistent AF (LPeAF) from non-LPeAF. A total of 224 AF patients were enrolled: 112 with PAF (87 males), 48 with PeAF (38 males), and 64 with LPeAF (47 males). The f-waves in surface ECG leads V1, aVL, and II, which reflect well electrical activity in the right atrium (RA), the left atrium (LA), and both atria, respectively, were analyzed. The f-waves for LPeAF had lower amplitudes in II and aVL, increased irregularity and a higher dominant rate in II and V1 compared to PAF and PeAF (all p < 0.02). In a multivariate analysis, a low amplitude in lead II (<34.6 uV) and high dominant rate in lead V1 (≧390/min) (p < 0.001) independently discriminated LPeAF from the other AF types. The f-waves combined with both a low amplitude in lead II and high dominant rate in lead V1 were significantly associated with LPeAF (OR 6.27, p < 0.001). Characteristics of the f-waves on the surface ECG could discriminate LPeAF from other types of AF.

Supplemental Content

Full text links

Icon for Nature Publishing Group Icon for PubMed Central
Loading ...
Support Center