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Saudi J Kidney Dis Transpl. 2019 Jan-Feb;30(1):254-257.

Minimal change disease and Kimura's disease responding to tacrolimus therapy.

Author information

1
Department of Nephrology, Jawaharlal Nehru Medical College, Wardha, Maharashtra, India.
2
Department of Nephrology, Government Medical College and Super Speciality Hospital, Nagpur, Maharashtra, India.
3
Department of Medicine, Northern Railway Central Hospital, New Delhi, India.

Abstract

Kimura's disease (KD) usually presents with a subcutaneous swelling and associated lymphadenopathy in the periauricular area. KD has a tendency to involve the kidneys. Proteinuria is reported in 12%-16% of cases, and around 60%-70% of them develop nephrotic range proteinuria. We are reporting a case of KD which developed around 12 years later in a patient of biopsy-proven steroid responsive minimal change disease. Recurrent swellings of KD and subnephrotic range proteinuria responded to low-dose tacrolimus therapy (0.05 mg/kg).

PMID:
30804291

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