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Saudi J Kidney Dis Transpl. 2019 Jan-Feb;30(1):254-257.

Minimal change disease and Kimura's disease responding to tacrolimus therapy.

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Department of Nephrology, Jawaharlal Nehru Medical College, Wardha, Maharashtra, India.
Department of Nephrology, Government Medical College and Super Speciality Hospital, Nagpur, Maharashtra, India.
Department of Medicine, Northern Railway Central Hospital, New Delhi, India.


Kimura's disease (KD) usually presents with a subcutaneous swelling and associated lymphadenopathy in the periauricular area. KD has a tendency to involve the kidneys. Proteinuria is reported in 12%-16% of cases, and around 60%-70% of them develop nephrotic range proteinuria. We are reporting a case of KD which developed around 12 years later in a patient of biopsy-proven steroid responsive minimal change disease. Recurrent swellings of KD and subnephrotic range proteinuria responded to low-dose tacrolimus therapy (0.05 mg/kg).


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