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Saudi J Kidney Dis Transpl. 2019 Jan-Feb;30(1):215-220.

Calciphylaxis in a renal transplant recipient with normal graft function: A case report and review of literature.

Author information

1
Department of Nephrology, Aditya Birla Memorial Hospital, Pune, Maharashtra, India.
2
Department of Pathology, Aditya Birla Memorial Hospital, Pune, Maharashtra, India.
3
Department of Nephrology, Deenanath Mangeshkar Hospital, Pune, Maharashtra, India.
4
Department of Medicine, Deenanath Mangeshkar Hospital, Pune, Maharashtra, India.
5
Department of Nephrology, Apollo Hospitals, Hyderabad, Telangana, India.
6
Department of Medicine, Harvard Medical School, Massachusetts General Hospital, Boston, USA.

Abstract

Calciphylaxis, also known as calcific uremic arteriolopathy, is a rare, life-threatening complication of end-stage renal disease. However, it may also occur in patients without renal failure, the nonuremic calciphylaxis. Most patients present with painful skin ulcers. Delayed diagnosis can lead to sepsis-related morbidity and mortality. Aberrations in calcium, phosphate, and parathyroid hormone physiology are common and biopsy is diagnostic. Early diagnosis and correction of vascular and metabolic aberrations may assist in healing as may the use of sodium thiosulfate and hyperbaric oxygen therapy. We report on successful treatment of a case of calciphylaxis in a renal transplant recipient with normal allograft function.

PMID:
30804284

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