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JCO Precis Oncol. 2018;2018. doi: 10.1200/PO.18.00190. Epub 2018 Nov 27.

Mismatch repair deficiency in high-grade meningioma: a rare but recurrent event associated with dramatic immune activation and clinical response to PD-1 blockade.

Author information

1
Department of Neurosurgery, Brigham and Women's Hospital, Boston, MA.
2
Department of Pathology, Brigham and Women's Hospital, Boston, MA.
3
Ludwig Center at Harvard Medical School, Boston, MA.
4
Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.
5
Department of Oncologic Pathology, Dana-Farber Cancer Institute, Boston, MA.
6
Department of Neurosurgery, Columbia University Medical Center, New York City, NY.
7
Department of Neurology, Brigham and Women's Hospital, Boston, MA.
8
Center for Neuro-Oncology, Dana-Farber Cancer Institute, Boston, MA.
9
Department of Informatics, Dana-Farber Cancer Institute, Boston, MA.
10
Center for Cancer Genome Discovery, Dana-Farber Cancer Institute, Boston, MA.
11
Department of Pathology and Cell Biology, Columbia University Medical Center, New York City, NY.
12
Foundation Medicine, Inc., Morrisville, NC.
13
Foundation Medicine, Inc., Cambridge, MA.
14
Department of Pathology, Wake Forest School of Medicine, Winston-Salem, NC.
15
Laboratory of Systems Pharmacology, Harvard Medical School, Boston, MA.
16
Department of Systems Biology, Harvard Medical School, Boston, MA.
#
Contributed equally

Conflict of interest statement

Disclosure of Potential Conflicts of Interest PKS is a member of the Scientific Advisory Board of RareCyte Inc., which manufactures the CyteFinder slide scanner used in this study. PKS is also co-founder of Glencoe Software, which contributes to and supports the open-source OME/OMERO image informatics software used in this paper. SS has consulted for RareCyte Inc..Other authors have no competing financial interests to disclose.

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