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Med Hypotheses. 2019 Mar;124:56-59. doi: 10.1016/j.mehy.2019.02.012. Epub 2019 Feb 2.

Field dynamics in atrioventricular activation. Clinical evidence of a specific field-to-protein interaction.

Author information

1
Department of Medicine, Faculty of Medicine, University of Lleida, Catalunya, Spain. Electronic address: mballesterr@gmail.com.
2
Cardiac Imaging Unit, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, CIBERCV, Spain.
3
Consorci Educació Barcelona, Diputació de Barcelona, Spain.
4
Consultant in Organic Chemistry, Biochemistry and Enzymology, Barcelona, Spain.
5
Al Sabah Arrythmia Institute, Mount Sinai St. Luke's Hospital, New York, USA.

Abstract

The atrioventricular node (AV) is considered the electrical connection between the atria and ventricles. There is an electrical pause between activation of the atria and the ventricles (PR segment), but to date the mechanism responsible for this interruption remains unclear. The present communication focuses on the hypothesis that magnetic field dynamics could provide the answer. Proof of this hypothesis is that in Wolff-Parkinson-White syndrome, where there is physical connection between the atria and ventricles (bundle of Kent), there is electrical AV continuity, no PR segment is detected, and catheter ablation of the abnormal bundle restores AV discontinuity. Spontaneous initiation of the heart at the level of the sinus node, the pacemaker of the heart, could also be explained via field dynamics. The known transmembrane pacemaker protein CHN4, present in both sinoatrial and AV nodal cells, could interact with field information to provide specificity in an electronic key-to-lock mechanism interaction.

KEYWORDS:

AV conduction; Atria; Atrioventricular delay; Atrioventricular node; Cardiac pacemaker; Cardiology; ECG; Electrocardiogram; Electromagnetism; Fields; Heart; Preexcitation; Quantum fields; Sinus node; Ventricles; Wolff-Parkinson-White

PMID:
30798917
DOI:
10.1016/j.mehy.2019.02.012
[Indexed for MEDLINE]

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