Format

Send to

Choose Destination
Stem Cell Res. 2019 Mar;35:101375. doi: 10.1016/j.scr.2018.101375. Epub 2018 Dec 18.

Generation of an integration-free iPSC line(SYSUi001-A) from a sporadic Alzheimer's disease patient.

Author information

1
Department of Neurology, The Sixth Affiliated Hospital of Sun Yat-Sen University, 26 Yuancun Erheng Rd, Guangzhou 510655, PR China.
2
Department of Psychiatry, The Third Affiliated Hospital of Sun Yat-Sen University, 600 Tianhe Rd, Guangzhou 510630, PR China.
3
Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, South China Institute for Stem Cell Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, PR China.
4
Department of Neurology, The Sixth Affiliated Hospital of Sun Yat-Sen University, 26 Yuancun Erheng Rd, Guangzhou 510655, PR China; Guangdong Province Key Laboratory of Brain Function and Disease, Zhongshan School of Medicine, Sun Yat-sen University, 74 Zhongshan 2nd Road, Guangzhou 510080, PR China; Shenzhen Research Institute of Sun Yat-Sen University, Southern District of Nanshan Science Park, Shenzhen 518019, PR China. Electronic address: lzhong@mail.sysu.edu.cn.

Abstract

Human iPSC line, iPSC-ADM01(SYSUi001-A), was generated from a 70-year-old male patient with sporadic Alzheimer's disease, using non-integrative reprogramming method. This cell line shows pluripotency both in vitro and in vivo, and has a normal karyotype.

PMID:
30797990
DOI:
10.1016/j.scr.2018.101375
Free full text

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center