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Mol Biol Rep. 2019 Apr;46(2):2541-2546. doi: 10.1007/s11033-019-04633-w. Epub 2019 Feb 22.

Forensic characteristics and phylogenetic structure of Eastern Chinese Han populations residing along the Yangtze Basin revealed by 19 autosomal STR loci.

Tao R1,2, Wang S1, Jin M3, Liu Y4, Zhang J2,5, Zhang S6, Li C7,8.

Author information

1
Institute of Forensic Medicine, West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu, 610041, People's Republic of China.
2
Shanghai Key Laboratory of Forensic Medicine, Shanghai Forensic Service Platform, Academy of Forensic Sciences, Ministry of Justice, P.R. China, Shanghai, 200063, People's Republic of China.
3
Public Security Bureau of Changzhou, Changzhou, 213022, People's Republic of China.
4
Jiangsu Province Hospital and Nanjing Medical University First Affiliated Hospital, Nanjing, 210029, People's Republic of China.
5
Department of Forensic Science, Medical School of Soochow University, Suzhou, 215123, People's Republic of China.
6
Shanghai Key Laboratory of Forensic Medicine, Shanghai Forensic Service Platform, Academy of Forensic Sciences, Ministry of Justice, P.R. China, Shanghai, 200063, People's Republic of China. zhangsh@ssfjd.cn.
7
Institute of Forensic Medicine, West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu, 610041, People's Republic of China. lict@ssfjd.cn.
8
Shanghai Key Laboratory of Forensic Medicine, Shanghai Forensic Service Platform, Academy of Forensic Sciences, Ministry of Justice, P.R. China, Shanghai, 200063, People's Republic of China. lict@ssfjd.cn.

Abstract

In present study, forensic parameters based on the population data of nineteen autosomal short tandem repeats (STRs) loci were estimated in Chinese Han populations from three riverfront areas of Yangtze Basin in Eastern China. The combined power of discrimination (CPD) were 0.9999999999999999999999883, 0.9999999999999999999999846 and 0.9999999999999999999999863, respectively. The combined power of exclusion (CPE) were 0.999999992248957, 0.999999989800400 and 0.999999989799819, respectively. Furthermore, the genetic relationships among our studied populations and 32 previously investigated populations residing in other areas of China were also analyzed based on pairwise genetic distances (FST). The multidimensional scaling (MDS) plot and phylogenetic tree indicated that our studied populations were majorly clustered with the Han populations along the Yangtze Basin and populations to the north of it. In summary, our results supported that the 19 autosomal STR loci, which were polymorphic and informative in forensic identification, could also be applied in population genetics studies.

KEYWORDS:

Eastern Chinese Han; Forensic genetics; Phylogenetic relationship; Short tandem repeat; Yangtze Basin

PMID:
30796649
DOI:
10.1007/s11033-019-04633-w

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