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Interv Med Appl Sci. 2018 Dec;10(4):233-235. doi: 10.1556/1646.10.2018.10.

The effects of branch-chain amino acids on fatigue in the athletes.

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Department of Physical Education and Sport Sciences, Parand Branch, Islamic Azad University, Tehran, Iran.
Faculty of Physical Education and Sport Sciences, South Tehran Branch, Islamic Azad University, Tehran, Iran.
Shiraz Branch, Islamic Azad University, Shiraz, Iran.


Research has shown that injection of a mixture of amino acids into humans led to stimulation of protein synthesis about 30 min after injection, and the synthesis rate remained at a high level for up to 90 min. Various theories have been proposed to justify this effect, such as increasing the availability of amino acids in the body to increase their transmission to muscle, and this increase in transmission can stimulate the synthesis of protein in muscle cells. A total of 30 volunteers with a history of 2-3 years in the field of Athletics were participated in this study. The experimental group (15 subjects) used BCAAs supplement during 6-week athletics training. Control group (15 subjects) participated in athletics training for 6 weeks without any supplementation. Blood was taken before and after 6 weeks supplementary. The findings of the t-test showed that basal levels of lactate and ammonium had not changed significantly after 42 days of supplementation. The results of this study showed that BCAAs supplementation has no effect on the reduction of lactate and ammonium indices as indicators of fatigue.


BCAAs; ammonium; athletics; exercise training; lactate

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