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Indian Dermatol Online J. 2019 Jan-Feb;10(1):13-18. doi: 10.4103/idoj.IDOJ_118_18.

A 10-year Retrospective Descriptive Study on Pure Neuritic Leprosy from a Tertiary Referral Centre.

Author information

1
Department of General Medicine, Government Medical College, Kozhikode, Kerala, India.
2
Department of Dermatology and Venereology, Government Medical College, Kozhikode, Kerala, India.
3
Department of Community Medicine, Government Medical College, Kozhikode, Kerala, India.
4
Health Services Department, Koyilandi Taluk Hospital, Koyilandy, Kerala, India.

Abstract

Context:

Pure neuritic leprosy is a risk factor for grade 2 disability owing to the early nerve damage.

Aims:

To study the clinical patterns of neuritic leprosy, to determine the percentage of patients manifesting grade 2 disability at the time of diagnosis and to identify any risk factors for the same.

Settings and Design:

Retrospective descriptive study from previous case records of pure neuritic leprosy patients who attended a tertiary centre from 1st July 2007 to 30th June 2017.

Subjects and Methods:

Data on patients who satisfied the World Health Organization (WHO) cardinal criteria for diagnosis of leprosy, who had no skin lesion of leprosy and had acid-fast bacilli negative status on skin smears were collected using a pre-set proforma.

Statistical Analysis Used:

The Chi-square test was used to assess statistical significance and logistic regression model was applied to avoid the effects of confounding factors.

Results:

A diagnostic delay of >1 year was observed in 44% patients. At the time of diagnosis, grade 2 disability was documented in 60 (80%) of patients. No statistically significant risk factor was identified for grade 2 disability.

Limitations:

Retrospective nature and the study conducted in a tertiary care centre not reflecting the status in the community were the limitations.

Conclusions:

Grade 2 disability noted in 80% of patients points to the inherent nature of disease to cause early nerve damage. Diagnostic delay of >1 year documented in 44% of patients underscores the diagnostic challenges in the absence of skin lesions.

KEYWORDS:

Grade 2 disability; neuritic leprosy; risk factor

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