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Circ Genom Precis Med. 2019 Feb;12(2):e002409. doi: 10.1161/CIRCGEN.118.002409.

Common Genetic Variation in Relation to Brachial Vascular Dimensions and Flow-Mediated Vasodilation.

Author information

1
Department of Internal Medicine (M.D., S.B.F.), University of Medicine Greifswald, Germany.
2
DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Germany (M.D., A.T., U.V., M.N., H.V., S.B.F.).
3
Department of Medicine, Sections of Cardiology and Vascular Medicine, Boston University School of Medicine, MA (N.M.H.).
4
Department of General & Interventional Cardiology, University of Heart Center Hamburg-Eppendorf, Germany (C.M., T.Z., S.B., R.B.S.).
5
DZHK (German Center for Cardiovascular Research), partner site Hamburg/Kiel/Lübeck, Germany (C.M., T.Z., S.B., R.B.S.).
6
Cardiovascular Health Research Unit, Department of Medicine, Epidemiology, & Health Services (N.L.S., B.M.P.), University of Washington, WA.
7
Kaiser Permanente Washington Health Research Institute (N.L.S., B.M.P.).
8
Seattle Epidemiologic Research and Information Center, Department of Veteran Affairs Office of Research and Development, WA (N.L.S.).
9
Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Sweden (S.G., L.L., E.I.).
10
Department of Clinical Chemistry, Fimlab Laboratories, and Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland (T.L., L.-P.L.).
11
Department SHIP/Clinical-Epidemiological Research, Institute for Community Medicine (A.T., H.V.), University of Medicine Greifswald, Germany.
12
Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, CA (X.L.).
13
Department of Clinical Physiology & Nuclear Medicine, Turku University Hospital, Finland (O.T.R.).
14
Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Finland (O.T.R.).
15
Department of Functional Genomics, Interfaculty Institute for Genetics & Functional Genomics (U.V.), University of Medicine Greifswald, Germany.
16
Cardiovascular Health Research Unit, Department of Biostatistics (B.M.), University of Washington, WA.
17
Department of Biostatistics, University of Liverpool, United Kingdom (A.P.M.).
18
Department of Clinical Physiology, Tampere University Hospital, and Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland (M.K.).
19
Department of Clinical Physiology, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Finland (M.K.).
20
Cardiovascular Health Research Unit, Department of Medicine (R.N.L.), University of Washington, WA.
21
Preventive Cardiology and Preventive Medicine, Center for Cardiology (P.S.W.), Department of Internal Medicine 2, University Medical Center of the Johannes Gutenberg-University Mainz, Germany.
22
Center for Thrombosis and Hemostasis (P.S.W.), Department of Internal Medicine 2, University Medical Center of the Johannes Gutenberg-University Mainz, Germany.
23
DZHK (German Center for Cardiovascular Research), partner site Rhine-Main, Mainz, Germany (P.S.W., T.M.).
24
Institute of Clinical Chemistry & Laboratory Medicine (M.N.), University of Medicine Greifswald, Germany.
25
Center for Cardiology (T.M.), Department of Internal Medicine 2, University Medical Center of the Johannes Gutenberg-University Mainz, Germany.
26
Department of Research, Cardiovascular Engineering Inc., Norwood, MA (G.F.M.).
27
Department of Research, Li Ka Shing Centre for Health Information and Discovery, The Big Data Institute (C.M.L.), University of Oxford, United Kingdom.
28
Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine (C.M.L.), University of Oxford, United Kingdom.
29
Broad Institute of the Massachusetts Institute of Technology & Harvard University, Cambridge, MA (C.M.L.).
30
Boston University and the NHLBI's Framingham Heart Study, MA (M.G.L., E.J.B.).
31
Department of Biostatistics, Boston University School of Public Health, MA (M.G.L.).
32
Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, CA (E.I.).
33
Stanford Cardiovascular Institute (E.I.), Stanford University, CA.
34
Stanford Diabetes Research Center (E.I.), Stanford University, CA.
35
Cardiovascular Medicine Department, Wake Forest University School of Medicine, Winston Salem, NC (D.H.).
36
Department of Medicine, Boston University School of Medicine and Department of Epidemiology, Boston University School of Public Health, Boston, MA (E.J.B.).

KEYWORDS:

brachial artery; dilation; epidemiology; genetics; genome-wide association study; insulin-like growth factor binding protein 3

PMID:
30779634
DOI:
10.1161/CIRCGEN.118.002409

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