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Indian J Med Res. 2018 Dec;148(6):748-751. doi: 10.4103/ijmr.IJMR_888_16.

A four year experience in narcolepsy from a sleep clinic at a tertiary care centre with a short review of contemporary Indian literature.

Author information

1
Department of Internal Medicine, All India Institute of Medical Sciences, New Delhi, India.

Abstract

Narcolepsy is a common sleep disorder in Western countries but rarely reported from India. Here, we report a small case series of four narcolepsy patients seen over a four year period in the sleep clinic of a tertiary care hospital in north India. The diagnosis was established by clinical history and two or more sleep-onset rapid eye movements (SOREMs) on multiple sleep latency tests (MSLTs) following overnight polysomnography (PSG). The mean age of patients was 26.2±6.4 yr; one patient had associated cataplexy and another one had all four cardinal symptoms of narcolepsy. All these patients had a history of excessive daytime sleepiness (EDS). The mean body mass index was 24.2±4.7 kg/m[2]. The mean sleep latency during MSLT was 2.7±1.3 min, and the mean REM latency was 5.7±2.9 min. Narcolepsy, although rarely reported from India, should be suspected in young non-obese patients complaining of EDS and confirmed by performing MSLT following overnight PSG.

KEYWORDS:

Multiple sleep latency test; narcolepsy; polysomnography; sleep-onset rapid eye movements

PMID:
30778010
DOI:
10.4103/ijmr.IJMR_888_16
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