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World J Nucl Med. 2019 Jan-Mar;18(1):63-65. doi: 10.4103/wjnm.WJNM_5_18.

Synchronous bilateral renal cell carcinomas in "Asynchrony of metabolism".

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Department of Nuclear Medicine and PET/CT, Yashoda Hospital, Hyderabad, Telangana, India.
Department of Radiology, Yashoda Hospital, Hyderabad, Telangana, India.
Department of Nuclear Medicine and PET/CT, Basavatarakam Indo-American Cancer Hospital, Hyderabad, Telangana, India.


Here, we present a case of bilateral synchronous renal cell carcinoma in a 52-year-old male patient, who underwent fluorodeoxyglucose positron emission tomography-computed tomography (FDG PET-CT) scan followed by surgical removal of both tumors. On PET scan, left renal mass showed intense FDG uptake while uptake in the right renal mass was minimal. Histopathologically, both tumors were conventional clear cell carcinoma (Fuhrman Grade III). Only the FDG-avid tumor in the left kidney had lymphovascular invasion and necrosis, which are markers of aggressive form of any tumor. FDG PET-CT can act as strong and noninvasive prognostic parameter that could help to identify patients with aggressive disease before treatment.


Fuhrman grade; lymphovascular invasion; positron emission tomography; renal cell carcinoma; synchronous primaries

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