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Toxicon. 2019 Mar 15;160:12-22. doi: 10.1016/j.toxicon.2019.02.001. Epub 2019 Feb 15.

Review: Biotechnology of mycotoxins detoxification using microorganisms and enzymes.

Author information

1
Laboratory of Analysis, Treatment and Valorization of Environmental Pollutants and Products, Faculty of Pharmacy, Monastir University, Tunisia.
2
College of Applied Medical Sciences, Medical Laboratory Department, Yanbu el Bahr, Taibah University, Saudi Arabia. Electronic address: bochrak@yahoo.fr.
3
College of Applied Medical Sciences, Medical Laboratory Department, Yanbu el Bahr, Taibah University, Saudi Arabia.
4
Laboratory of Genetic, Biodiversity and Bio-Ressources Valorization, Higher Institute of Biotechnology, Monastir University, Tunisia.

Abstract

Mycotoxins are secondary metabolites produced by various toxigenic fungi belonging to the genera Aspergillus, Fusarium and Penicillium. They have mutagenic, teratogenic, carcinogenic, immunosuppressive and endocrine disrupting effects on both humans and animals. The ubiquitous occurrence and heat stability of these mycotoxins during food and feed processing pose serious health problems in human and animals. Therefore successful biotechnological detoxification tools are in great demand. Recently, the use of bacteria, yeast, moulds and enzymes to mitigate/bind or biodegrade various mycotoxins is a novel strategy used for mycotoxins removal. In this review, recent development in biological control of mycotoxins removal and detoxification will be discussed.

KEYWORDS:

Bacteria; Binding; Detoxification; Enzymes; Fungi; Mycotoxins; Yeast

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