Format

Send to

Choose Destination
J Oncol Pract. 2019 Feb;15(2):81-90. doi: 10.1200/JOP.18.00483.

Oral Anticancer Therapy: Management of Drug Interactions.

Author information

1
1 University of Rhode Island, Kingston, RI.
2
2 New York-Presbyterian Hospital, New York.
3
3 UPMC Presbyterian, Pittsburgh, PA.
4
4 Roswell Park Cancer Institute, Buffalo, NY.
5
5 Allegheny Health Network, Pittsburgh, PA.

Abstract

Oral anticancer therapy is increasingly integrated into the care of patients with cancer. Recognition and management of drug-drug interactions (DDIs) is critical to providing efficacious and safe anticancer treatment. DDIs with QTc-prolonging agents, anticoagulants, enzyme inducers and inhibitors, antidepressants, and acid suppressants are commonly encountered with anticancer therapies. Here, we review frequently observed DDIs and outline literature-supported suggestions for their management.

PMID:
30763198
DOI:
10.1200/JOP.18.00483

Supplemental Content

Full text links

Icon for Atypon
Loading ...
Support Center