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J Bone Jt Infect. 2019 Jan 29;4(1):50-55. doi: 10.7150/jbji.30615. eCollection 2019.

Metagenomic next-generation sequencing contribution in identifying prosthetic joint infection due to Parvimonas micra: a case report.

Author information

1
Department of Orthopedic Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou 350004, China.
2
BGI Genomics, BGI-Shenzhen, Shenzhen 518083, China.
3
Department of Laboratory Medicine, The First Affiliated Hospital of Fujian Medical University, Fuzhou 350004, China.

Abstract

Identifying fastidious pathogens in patients with prosthetic joint infection (PJI) by culture is challenging. Metagenomic next-generation sequencing (mNGS) is a novel culture-independent approach that is associated with a higher likelihood for identifying pathogens. We present a case where mNGS was implemented to identify Parvimonas micra, a rarely reported and difficult-to-culture PJI pathogen.

KEYWORDS:

Metagenomic next-generation sequencing; Parvimonas micra; Prosthetic joint infection

Conflict of interest statement

Competing Interests: The authors have declared that no competing interest exists.

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