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J Bone Jt Infect. 2019 Jan 1;4(1):16-19. doi: 10.7150/jbji.30256. eCollection 2019.

Same Organism, Different Phenotype - Are Phenotypic Criteria Adequate In Coagulase-Negative Staphylococcal Orthopaedic Implant-Associated Infections?

Author information

1
Department of Infectious Diseases, Karlstad, and Centre for Clinical Research, County Council of Värmland, Sweden.
2
School of Medical Sciences, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
3
Department of Bacteria, Parasites and Fungi, Statens Serum Institut, Copenhagen, Denmark.
4
Department of Infectious Diseases and Department of Clinical and Experimental Medicine, Linköping University, Norrköping, Sweden.

Abstract

In current diagnostic criteria for implant-associated bone- and joint infections, phenotypically identical low-virulence bacteria in two intraoperative cultures are usually required. Using whole-genome sequencing, we have further characterized three phenotypically different Staphylococcus capitis isolated from one prosthetic joint infection, highlighting the challenges in defining microbiological criteria for low-virulence prosthetic joint infections.

Conflict of interest statement

Competing Interests: The authors have declared that no competing interest exists.

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