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Mol Cell. 2019 Feb 7;73(3):392-394. doi: 10.1016/j.molcel.2019.01.030.

Pach-ing It in: The Peculiar Organization of Mammalian Pachytene Chromosomes.

Author information

1
Department of Biology, Emory University, 1510 Clifton Road NE, Atlanta, GA 30322, USA.
2
Department of Biology, Emory University, 1510 Clifton Road NE, Atlanta, GA 30322, USA. Electronic address: vgcorces@gmail.com.

Abstract

In this issue of Molecular Cell, Wang et al. (2019) use Hi-C to visualize at high resolution the complex reprogramming of chromatin architecture during spermatogenesis in rhesus monkeys and mice. They find that pachytene spermatocytes have a unique chromosome organization that may result from the presence of the synaptonemal complex and transcription-associated proteins.

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