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Cell Stem Cell. 2019 Feb 7;24(2):206-207. doi: 10.1016/j.stem.2019.01.005.

Setting our AdipoSIGHTS on Stem Cells in Pharmacogenomics.

Author information

1
Leipzig University Medical Center, IFB AdiposityDiseases, University of Leipzig, 04103, Leipzig, Germany; Division of Endocrinology, Nephrology and Rheumatology, University of Leipzig, 04103, Leipzig, Germany. Electronic address: peter.kovacs@medizin.uni-leipzig.de.

Abstract

In a recent study published in Cell Stem Cell, Hu et al. (2019) used human adipose stem cell-derived adipocytes to demonstrate that genetic variation predicts anti-diabetic response to thiazolidinediones (TZDs) by modulating PPARγ binding.

PMID:
30735647
DOI:
10.1016/j.stem.2019.01.005

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