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Acad Pathol. 2019 Jan 10;6:2374289518820337. doi: 10.1177/2374289518820337. eCollection 2019 Jan-Dec.

Educational Case: Primary Osteosarcoma.

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Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA.
Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.


The following fictional case is intended as a learning tool within the Pathology Competencies for Medical Education (PCME), a set of national standards for teaching pathology. These are divided into three basic competencies: Disease Mechanisms and Processes, Organ System Pathology, and Diagnostic Medicine and Therapeutic Pathology. For additional information, and a full list of learning objectives for all three competencies, see


bone; bone neoplasia; malignant bone tumors; musculoskeletal; organ system pathology; osteosarcoma; osteosarcoma risk factors; osteosarcoma staging; pathology competencies; primary bone tumors; tumor staging

Conflict of interest statement

Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

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