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Neurotoxicol Teratol. 1988 Sep-Oct;10(5):475-8.

Parkinsonism: a clinical marker of exposure to neurotoxins.

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1
Johns Hopkins University School of Medicine, Department of Neurology, Francis Scott Key Medical Center, Baltimore, MD 21224.

Abstract

Parkinson must be viewed as a final common pathway resulting from a variety of neuropathological lesions which interfere with the integrity of the nigrostriatal system or its output. Exposure to a wide variety of neurotoxic compounds, namely, carbon monoxide, carbon disulfide, manganese and MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine), are associated with parkinsonism that has a varying neuropathology, which will be discussed.

PMID:
3073307
[Indexed for MEDLINE]
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