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Ann Emerg Med. 2019 Feb 4. pii: S0196-0644(18)31576-2. doi: 10.1016/j.annemergmed.2018.12.012. [Epub ahead of print]

Clinical Practice Guideline for Emergency Department Procedural Sedation With Propofol: 2018 Update.

Author information

1
Division of Emergency Medicine, Boston Children's Hospital, and the Department of Pediatrics, Harvard Medical School, Boston, MA. Electronic address: kelsey.miller@childrens.harvard.edu.
2
Department of Emergency Medicine, Lions Gate Hospital, North Vancouver, British Columbia, Canada.
3
Department of Emergency Medicine, Hennepin County Medical Center, Minneapolis, MN.
4
Department of Emergency Medicine, Carilion Clinic, Virginia Tech Carilion School of Medicine, Roanoke, VA.
5
Division of Emergency Medicine, Boston Children's Hospital, and the Department of Pediatrics, Harvard Medical School, Boston, MA.

Abstract

We update an evidence-based clinical practice guideline for the administration of propofol for emergency department procedural sedation. Both the unique considerations of using this drug in the pediatric population and the substantial new research warrant revision of the 2007 advisory. We discuss the indications, contraindications, personnel requirements, monitoring, dosing, coadministered medications, and adverse events for propofol sedation.

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