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Clin Pharmacokinet. 1988 Dec;15(6):355-66.

Clinical pharmacokinetics of doxycycline and minocycline.

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Unité de Pharmacocinétique Clinique, CHU Purpan, Toulouse, France.


Doxycycline and minocycline are second-generation tetracyclines. They are readily absorbed, distributed throughout the organism as a function of their lipophilicity and eliminated in both the urine and the faeces. The influence of age, renal disease, malnutrition and hyperlipidaemia is reviewed, together with the main pharmacokinetic interactions.

[Indexed for MEDLINE]

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