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Ned Tijdschr Geneeskd. 2019 Jan 30;163. pii: D3417.

[Ring-shaped lesions on a lung scan].

[Article in Dutch]

Author information

1
Radboudumc, afd. Hematologie, Nijmegen.
2
Radboudumc, afd. Nucleaire Geneeskunde, Nijmegen.
3
Contact: W.J.F.M. van der Velden (walter.vandervelden@radboudumc.nl).

Abstract

A 25-year-old man was treated with pembrolizumab for a relapsed-refractory primary mediastinal large B-cell lymphoma. On an evaluation PET-CT scan multiple 'reversed halo signs' were noticed. No infectious cause was established and we diagnosed the lesions as pembrolizumab-induced pneumonitis, an immune-related adverse event.

PMID:
30719883

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