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Am J Intellect Dev Disabil. 2019 Jan;124(1):4-10. doi: 10.1352/1944-7558-124.1.4.

The Prevalence of OSA Among an Adult Population With Down Syndrome Referred to a Medical Clinic.

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Michelle Cornacchia, Geisinger Health System; Janis Sethness and Philip Alapat, Baylor College of Medicine; Yu-Hsiang Lin, UCLA Health; and Cynthia Peacock, Baylor College of Medicine.


Obstructive sleep apnea (OSA) is a common sleep disorder affecting approximately 16% of adults (24% of men and 9% of women), and, if untreated, it can cause significant complications ( Young, 2009 ). This study evaluates 56 adult patients with Down syndrome and analyzed retrospective data to determine the: (1) prevalence of OSA, (2) severity of OSA, and (3) association between body mass index (BMI) and OSA. Of those participants that had polysomnography (PSG) testing available, 82.1% were diagnosed with OSA, divided by severity into mild (45.7%), moderate (15.2%), and severe (39.1%) levels. Because of the high prevalence of OSA among our study population, we recommend that all adults with DS be screened for OSA with PSG.



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