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Indian J Nucl Med. 2019 Jan-Mar;34(1):42-44. doi: 10.4103/ijnm.IJNM_102_18.

Isolated Fluorodeoxyglucose Avid Right Pleural Deposits/Effusion on an F-18 Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in Patients with Ovarian Cancer - Are they almost Certainly Metastatic? An Extrapolation of Atypical Meigs' Syndrome.

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Department of Nuclear Medicine and PET/CT, VPS Lakeshore Hospital, Kochi, Kerala, India.
Department of Radiology, VPS Lakeshore Hospital, Kochi, Kerala, India.
Department of Surgical Oncology, VPS Lakeshore Hospital, Kochi, Kerala, India.


Majority of ovarian cancer (OC) patients are usually diagnosed at advanced stage and present with peritoneal spread/ascites. Some patients develop pleural deposits/effusion secondary to transdiaphragmatic spread of peritoneal disease/ascites. However, pleural deposits/effusion from OC in the absence of peritoneal disease/ascites are very rare. We present a case of serous carcinoma of the left ovary with fluorodeoxyglucose (FDG) avid right pleural deposits and effusion in the absence of peritoneal disease/ascites on FDG positron emission tomography (PET)/computed tomography (CT), showing excellent response to chemotherapy in subsequent PET/CT. We also discuss the pathophysiology of pleural abnormalities in patients with ovarian diseases, a characteristic disease spread pattern and recognition of which would help in the imaging interpretation.


Atypical Meigs’ syndrome; Meigs’ syndrome; ovarian malignancy; pleural metastases

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