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Sci Immunol. 2019 Feb 1;4(32). pii: eaaw3345. doi: 10.1126/sciimmunol.aaw3345.

A perfect storm: Genetics and anticommensal antibodies shore up type 1 diabetes.

Luber JM1,2,3,4, Kostic AD1,2,4.

Author information

1
Section on Pathophysiology and Molecular Pharmacology, Joslin Diabetes Center, Boston, MA 02215, USA. jluber@g.harvard.edu aleksandar.kostic@joslin.harvard.edu.
2
Section on Islet Cell and Regenerative Biology, Joslin Diabetes Center, Boston, MA 02215, USA.
3
Division of Medical Sciences, Harvard Medical School, Boston, MA 02115, USA.
4
Department of Microbiology, Harvard Medical School, Boston, MA 02115, USA.

Abstract

HLA haplotypes in conjunction with serum anticommensal antibody responses are predictive of type 1 diabetes progression. See related Research Article by Paun et al.

PMID:
30709844
DOI:
10.1126/sciimmunol.aaw3345

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