Prognostication in Mesenchymal Tumors: Can We Improve?

Surg Pathol Clin. 2019 Mar;12(1):217-225. doi: 10.1016/j.path.2018.10.009. Epub 2018 Dec 4.

Abstract

Prognostication in mesenchymal tumors can be challenging. They exhibit diverse, and sometimes overlapping, histologic features that are not always predictive of their true behavior. This article highlights examples of both traditional and emerging sarcoma biomarkers.

Keywords: Biomarker; Prognostic; Sarcoma.

Publication types

  • Review

MeSH terms

  • Biomarkers, Tumor / genetics
  • DNA Methylation
  • Humans
  • Immunohistochemistry
  • Mesenchymoma / diagnosis*
  • Mesenchymoma / genetics
  • Mesenchymoma / pathology*
  • Oncogene Proteins, Fusion / genetics
  • Prognosis
  • Soft Tissue Neoplasms / diagnosis*
  • Soft Tissue Neoplasms / genetics
  • Soft Tissue Neoplasms / pathology*
  • Translocation, Genetic

Substances

  • Biomarkers, Tumor
  • Oncogene Proteins, Fusion