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Pediatr Pulmonol. 2019 Apr;54(4):E10-E12. doi: 10.1002/ppul.24262. Epub 2019 Jan 31.

Macrophage activation syndrome due to Nocardia spp in a pediatric patient with cystic fibrosis.

Author information

1
Department of Pediatric Pulmonology, Dr Sami Ulus Maternity and Children Research and Training Hospital, Ankara, Turkey.
2
Faculty of Medicine, Department of Pediatric Pulmonology, Gazi University, Ankara, Turkey.
3
Faculty of Medicine, Department of Pediatric Hematology, Gazi University, Ankara, Turkey.
4
Faculty of Medicine, Department of Pediatric Infectious Disease, Gazi University, Ankara, Turkey.

Abstract

Nocardia spp is a gram-positive aerobic filamentous bacteria that causes pulmonary and systemic infections, especially in patients with immunosuppression or chronic lung diseases. It is rarely reported in children with cystic fibrosis. Macrophage activation syndrome is a life-threatening disease with an excessive inflammatory response usually triggered by infections. There are few reports in cystic fibrosis related to macrophage activation syndrome. Herein we report a child with cystic fibrosis who had macrophage activation syndrome due to Nocardia infection.

KEYWORDS:

child; cystic fibrosis; macrophage activation syndrome; nocardia

PMID:
30706673
DOI:
10.1002/ppul.24262

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