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Catheter Cardiovasc Interv. 2019 Jun 1;93(7):E381-E384. doi: 10.1002/ccd.28092. Epub 2019 Jan 31.

Intracoronary recombinant tissue plasminogen activator in an infant with hypoplastic left heart syndrome and complete left main coronary artery thrombosis.

Author information

1
Congenital Heart Center, Spectrum Health Helen DeVos Children's Hospital, Grand Rapids, Michigan.
2
West Michigan Anesthesia, PC, Grand Rapids, Michigan.
3
College of Human Medicine, Michigan State University, Grand Rapids, Michigan.

Abstract

An infant with hypoplastic left heart syndrome (HLHS) presented with complete heart block and severe myocardial dysfunction requiring ECMO support due to complete left main coronary artery (LMCA) thrombosis. Current guidelines for managing coronary artery thrombosis in infants with single ventricle physiology are inadequate. We describe successful LMCA and branch recanalization via intra coronary infusion of recombinant tissue plasminogen activator and discuss management of acute coronary thrombosis in children with single ventricle physiology.

KEYWORDS:

congenital heart disease; coronary artery; plasminogen activator; recanalization; thrombosis

PMID:
30702202
DOI:
10.1002/ccd.28092

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