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Indian J Cancer. 2018 Jul-Sep;55(3):304-305. doi: 10.4103/ijc.IJC_260_18.

Gastrointestinal mucormycosis in a child with acute lymphoblastic leukemia: An uncommon but ominous complication.

Author information

1
Department of Medical Oncology, Cancer Institute (WIA), Chennai, Tamil Nadu, India.
2
Department of Oncopathology, Cancer Institute (WIA), Chennai, Tamil Nadu, India.
3
Department of Surgical Oncology, Cancer Institute (WIA), Chennai, Tamil Nadu, India.

Abstract

Invasive fungal infections constitute a major cause of morbidity and mortality in children undergoing therapy for hematological malignancies. We report a 1-year-old boy who was receiving chemotherapy for acute lymphoblastic leukemia. His clinical course was complicated by a clinical syndrome consistent with neutropenic enterocolitis to which he succumbed. Histopathology of the surgically resected bowel revealed evidence of mucormycosis. Gastrointestinal mucormycosis is an unusual presentation which requires high degree of clinical suspicion and aggressive management.

KEYWORDS:

Bowel gangrene; mucor; multi-drug resistant infection; neutropenic colitis; zygomycosis

PMID:
30693900
DOI:
10.4103/ijc.IJC_260_18
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