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Asian J Transfus Sci. 2018 Jul-Dec;12(2):154-156. doi: 10.4103/ajts.AJTS_86_17.

Severe hypertriglyceridemia-induced pancreatitis successfully managed with therapeutic plasma exchange: Report from India.

Author information

1
Department of Transfusion Medicine, Medanta - The Medicity, Gurgaon, Haryana, India.
2
Department of Gastroenterology and Hepatology, Medanta - The Medicity, Gurgaon, Haryana, India.

Abstract

Hypertriglyceridemia (HTG) is the third most significant risk factor for acute pancreatitis after gallstones and alcohol. Therapeutic plasma exchange (TPE) has been considered a possible treatment for HTG-induced pancreatitis, especially in severe and refractory cases. Here, we report one such clinical experience with a patient of severe HTG-induced pancreatitis. He was treated with TPE along with intravenous insulin, statins, and fibrates. TPE resulted in immediate relief of symptoms as well as a marked improvement in laboratory values, with 74.5% reduction in triglycerides after a single session. TPE can be successfully utilized as an adjunct in HTG-induced pancreatitis.

KEYWORDS:

Hypertriglyceridemia; pancreatitis; therapeutic plasma exchange

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