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Asian J Transfus Sci. 2018 Jul-Dec;12(2):123-126. doi: 10.4103/ajts.AJTS_119_17.

Intra- and inter-model reliability of Hemocue Hb 201+ and HemoCue Hb 301 devices.

Author information

1
Department of Immunohematology and Blood Transfusion, Himalayan Institute of Medical Sciences, SRHU, Dehradun, Uttarakhand, India.
2
Department of Pathology and Laboratory Medicine, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
3
All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.

Abstract

AIM:

The study intended to estimate the intra- and inter-model reliability and agreement between the HemoCue Models 201+ and 301 in a blood bank donor screening setting.

MATERIALS AND METHODS:

Venous blood samples from 115 blood donors were analyzed by two Hemocue 201+ instruments and two HemoCue 301 instruments. The Lin's concordance correlation coefficient (CCC) as well as the Bland-Altman limits of agreement was measured.

RESULTS:

The 95% lower confidence interval (CI) of all the CCCs had a value >0.90. The CCC between instruments belonging to the same model was compared to instruments belonging to different models. The mean of HemoCue 301 was higher than HemoCue 201+ by 3.04 g/L with the 95% CI of the differences (i.e., the limits of agreement) between the two models ranging from -3.35 to 9.44 g/L. The bias between two instruments was lesser, and the limits of agreement were even narrower between instruments belonging to the same model.

CONCLUSION:

The inter-instrument reliability and agreement are satisfactory in a blood bank setting.

KEYWORDS:

Anemia; hemoglobin; method comparison; point-of-care testing; reliability

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