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Ann Thorac Surg. 2019 Jan 25. pii: S0003-4975(19)30117-1. doi: 10.1016/j.athoracsur.2018.12.046. [Epub ahead of print]

Mitral Valve Endocarditis: A rare Manifestation of Lyme Disease.

Author information

1
Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic Foundation, Cleveland, Ohio. Electronic address: haddado@ccf.org.
2
Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic Foundation, Cleveland, Ohio.
3
Department of Infectious Disease, Cleveland Clinic Foundation, Cleveland, Ohio.

Abstract

Valvular involvement in Lyme disease is rare. Confirmation of Borrelia species as the causative agent by Polymerase Chain Reaction (PCR) was done in a few cases in Europe and the US. We describe a case of mitral regurgitation with a preoperative diagnosis of myxomatous mitral valve degeneration. During surgery, the surgeon suspected infective rather than degenerative; etiology; tissue cultures were negative. However, universal bacterial PCR on explanted valve tissue detected Borrelia burgdorferi Deoxyribonucleic Acid(DNA). If a surgeon suspects infective endocarditis at the time surgery, appropriate specimens should be sent for histopathology, culture, and PCR.

KEYWORDS:

Borrelia burgdorferi; Infective Endocarditis; Lyme Carditis

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