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Clin Infect Dis. 2019 Jan 28. doi: 10.1093/cid/ciz048. [Epub ahead of print]

Risk of Latent Tuberculosis Reactivation after Hematopoietic-Cell Transplantation.

Cheng MP1,2,3, Kusztos AE1,2, Bold TD1,3,4, Ho VT2,3, Glotzbecker BE2,3, Hsieh C2, Baker MA1,2,3, Baden LR1,2,3, Hammond SP1,2,3, Marty FM1,2,3.

Author information

1
Division of Infectious Diseases, Brigham and Women's Hospital, Boston, MA.
2
Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.
3
Harvard Medical School, Boston, MA.
4
Division of Infectious Diseases and International Medicine, University of Minnesota, Minneapolis, MN.

Abstract

There were no cases of tuberculosis in a cohort of 2531 patients who underwent hematopoietic-cell transplantation from 2010 to 2015 after 7323 person-years of follow up (95%CI, 0.0-0.05 cases/100 person-years), including 29 (1.15%) patients with untreated latent tuberculosis pre-transplantation after 89 person-years of follow up (95% CI, 0.0-4.06 cases/100 person-years).

PMID:
30689792
DOI:
10.1093/cid/ciz048

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