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Clin Infect Dis. 2019 Aug 16;69(5):869-872. doi: 10.1093/cid/ciz048.

Risk of Latent Tuberculosis Reactivation After Hematopoietic cell Transplantation.

Cheng MP1,2,3, Kusztos AE1,2, Bold TD1,3,4, Ho VT2,3, Glotzbecker BE2,3, Hsieh C2, Baker MA1,2,3, Baden LR1,2,3, Hammond SP1,2,3, Marty FM1,2,3.

Author information

1
Division of Infectious Diseases, Brigham and Women's Hospital.
2
Department of Medical Oncology, Dana-Farber Cancer Institute.
3
Harvard Medical School, Boston, Massachusetts.
4
Division of Infectious Diseases and International Medicine, University of Minnesota, Minneapolis, Minnesota.

Abstract

There were no cases of tuberculosis in a cohort of 2531 patients who underwent hematopoietic cell transplantation from 2010 to 2015 after 7323 person-years of follow up (95% confidence interval [CI], 0.0-0.05 cases/100 person-years), including 29 (1.15%) patients with untreated latent tuberculosis after 89 person-years of follow-up (95% CI, 0.0-4.06 cases/100 person-years).

KEYWORDS:

Mycobacterium tuberculosis ; LTBI; TB; allogeneic; hematopoietic cell transplantation

PMID:
30689792
PMCID:
PMC6938207
[Available on 2020-03-28]
DOI:
10.1093/cid/ciz048

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