Format

Send to

Choose Destination
J Gen Intern Med. 2019 Jun;34(6):978-985. doi: 10.1007/s11606-018-4820-0. Epub 2019 Jan 25.

Factors Affecting Adherence in a Pragmatic Trial of Annual Fecal Immunochemical Testing for Colorectal Cancer.

Author information

1
Kaiser Permanente Center for Health Research, 3800 N. Interstate Ave., Portland, OR, 97227, USA.
2
Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA.
3
Kaiser Permanente Center for Health Research, 3800 N. Interstate Ave., Portland, OR, 97227, USA. gloria.d.coronado@kpchr.org.

Abstract

BACKGROUND:

Colorectal cancer screening by fecal immunochemical test (FIT) reduces the burden of colorectal cancer. However, effectiveness relies on annual adherence, which presents challenges for clinic staff and patients.

OBJECTIVE:

Describe FIT return rates and identify factors associated with FIT adherence over 2 years in a mailed FIT outreach program in federally qualified health centers.

DESIGN:

Observational study nested in the Strategies and Opportunities to Stop Colon Cancer in Priority Populations (STOP CRC) trial. Five thousand one hundred ninety-five patients had an initial FIT order and were followed for ≥ 2 years (3574 also had a FIT order in the second year).

MAIN MEASURES:

FIT return percent in each year and patient- and neighborhood-level characteristics associated with FIT adherence.

KEY RESULTS:

Overall, the proportion of FIT orders that were completed was 46% in the patients' first year and 41% in the patients' second year. Of the 5195 patients with a FIT order in year 1, 3574 (69%) also had a FIT order in year 2 (71% of year 1 adherers and 67% of year 1 non-adherers, p = 0.009). Among those with a FIT order in the second year, the FIT return rate was about twice as high among those who were adherent in the first year (952/1674, or 57%) as among those who were not (531/1900, or 28%, p < 0.0001). Patient-level characteristics associated with higher odds of FIT return were a history of FIT screening at baseline, age over 65 (vs 50-65), no current tobacco use, recent receipt of a mammogram or flu vaccine, Asian ancestry (compared to non-Hispanic white), and non-English preference. The only neighborhood factor associated with lower FIT return rate was patient's larger residential city size.

CONCLUSION:

Our findings can inform the customization of programs to promote FIT return among patients who receive care at federally qualified health centers.

TRIAL REGISTRATION:

http://www.clinicaltrials.gov.

KEYWORDS:

cancer; colorectal; fecal immunochemical test; screening

PMID:
30684199
PMCID:
PMC6544723
[Available on 2020-06-01]
DOI:
10.1007/s11606-018-4820-0

Supplemental Content

Full text links

Icon for Springer
Loading ...
Support Center