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J Assist Reprod Genet. 2019 Jan 25. doi: 10.1007/s10815-019-01407-y. [Epub ahead of print]

Obstetrical complications of thin endometrium in assisted reproductive technologies: a systematic review.

Author information

1
Department of OB/GYN, University of Miami/Jackson Memorial Hospital, Miami, FL, USA. ymouhayar@med.miami.edu.
2
IVI RMA New Jersey, Basking Ridge, NJ, USA.
3
Virginia Center for Reproductive Medicine, Reston, VA, USA.
4
Department of OB/GYN, George Washington University, Washington, DC, USA.

Abstract

PURPOSE:

The aim of the systematic review is to describe the obstetrical complications associated with pregnancies in the context of a thin endometrial lining.

METHODS:

Systematic review of the literature.

RESULTS:

Patients who conceive in the setting of a thin endometrium have a significantly increased risk of early pregnancy loss, namely miscarriage and ectopic pregnancy. These patients also have a twofold increase in low birth weight and preterm delivery, as well as a significantly higher risk of intrauterine growth restriction and composite adverse perinatal outcomes.

CONCLUSIONS:

In addition to the lower probability of conception, a thin endometrium in assisted reproductive technologies appears to be associated with both early and late pregnancy complications. These pregnancies thus warrant special attention and close follow-up from obstetricians.

KEYWORDS:

Ectopic pregnancy; Low birth weight; Miscarriage; Obstetrical complications; Preterm delivery; Thin endometrium

PMID:
30684071
DOI:
10.1007/s10815-019-01407-y

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