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Environ Sci Pollut Res Int. 2019 Mar;26(8):7752-7762. doi: 10.1007/s11356-018-04113-x. Epub 2019 Jan 23.

Effects of cadmium exposure on antioxidant enzymes and histological changes in the mud shrimp Austinogebia edulis (Crustacea: Decapoda).

Author information

1
Institute of Marine Biology, National Taiwan Ocean University, Keelung, Taiwan.
2
LOG, Laboratoire d'Océanologie et de Géosciences, University of Lille, CNRS, Universite Littoral Cote d'Opale, UMR 8187, 62930, Wimereux, France.
3
Department of Pathology, Mackay Memorial Hospital, Danshuei District, New Taipei City, 25160, Taiwan.
4
School of Life Sciences, Shanxi University, Taiyuan, China.
5
Institute of Marine Biology, National Taiwan Ocean University, Keelung, Taiwan. jshwang@mail.ntou.edu.tw.
6
Center of Excellence for the Oceans, National Taiwan Ocean University, Keelung, Taiwan. jshwang@mail.ntou.edu.tw.

Abstract

The trace metal cadmium (Cd) is a toxic pollutant known to induce oxidative stress and other sublethal to lethal effects on aquatic organisms. We exposed the marine mud shrimp Austinogebia edulis to Cd concentrations of 0, 0.5, and 5 mg/kg for up to 4 days (24, 48, 72, 96 h). We studied the activity of antioxidant enzymes in the hepatopancreas, gill, and muscle of A. edulis. Antioxidant enzymes (SOD, CAT, and GPx) decreased with increasing Cd concentration and extended exposure time in these three organs of the mud shrimp A. edulis. Increasing Cd concentration led to an increase in ROS and resulted ultimately in membrane lipid peroxidation at higher Cd concentrations. Significant damage of the hepatopancreas of A. edulis was noticed at higher concentrations of Cd, showing damages like the disappearance of epithelial cell boundaries, detachment of cells from the basal lamina, cellular swelling, necrosis, and reduction of glycogen. In conclusion, Cd caused oxidative damage by reducing the activities of antioxidant enzymes and by damaging the tissue structure in major organs of the mud shrimp A. edulis.

KEYWORDS:

Antioxidant enzyme; Austinogebia edulis; Cadmium; Gill; Hepatopancreas; Mud shrimp; Muscle; Oxidative damage

PMID:
30673948
DOI:
10.1007/s11356-018-04113-x
[Indexed for MEDLINE]

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