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Herz. 2019 Feb;44(1):45-52. doi: 10.1007/s00059-019-4782-y.

[Acute coronary syndrome : Prevention].

[Article in German]

Author information

European Prevention Center im Medical Center Düsseldorf (GrandArc), Luise-Rainer-Str. 6-10, 40235, Düsseldorf, Deutschland.
Praxis für Gefäß- und Herzmedizin, Neustadt a. d. Weinstraße, Deutschland.
Abteilung 1 (Kardiologie, Diabetologie), Paracelsus-Harz-Klinik Bad Suderode, Quedlinburg, Deutschland.


For life style modifications primary and secondary prevention of acute coronary syndrome (ACS) are approximately similar, even though in the postinfarction situation functional diagnostic programs have to be performed in a rehabilitative manner. All three life style pillars of fitness, nutrition and relaxation implicate prognostic significance and the efficacy is higher for secondary prevention than for primary. The pharmacotherapeutic indications for thrombocyte aggregation inhibition are connected to the presence of atherosclerosis and statin medication is already connected to cardiovascular risk factor stratification, for which scores are used. Depending on the postinfarction myocardial destruction after ACS, additional pharmacotherapies, such as angiotensin-converting enzyme (ACE) inhibitors, angiotensin-II receptor antagonists, beta blockers and also mineral corticoid receptor antagonists are evident. New potential for prevention is ascribed to the new oral anticoagulants (NOAC) in the context of coincidental atrial fibrillation.


Atherosclerosis; Life style; Myocardial infarction; Platelet aggregation; Risk factors

[Indexed for MEDLINE]

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