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J Clin Transl Endocrinol Case Rep. 2018 Dec;10:1-3. doi: 10.1016/j.jecr.2018.07.003. Epub 2018 Aug 2.

Case of reversible diabetes mellitus in the setting of benign Pheochromocytoma.

Author information

1
Department of Medicine, Division of Diabetes, Endocrinology, and Metabolism, Vanderbilt University Medical Center, Nashville, TN, USA.
2
Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.
3
Department of Surgery, Division of Surgical Oncology and Endocrine Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.

Abstract

Pheochromocytomas have been shown to impair glucose tolerance and, rarely, to precipitate overt diabetes mellitus. We report here a case of a large pheochromocytoma in a woman with a recent diagnosis of diabetes mellitus that proved difficult to control despite high-dose insulin therapy who had complete resolution of her hyperglycemia following adrenalectomy. Her dramatic presentation demonstrates the need to consider this etiology in patients with new-onset insulin resistance and hypertension.

KEYWORDS:

Diabetes mellitus; Impaired glucose tolerance; Insulin resistance; Pheochromocytoma

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