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SPAG5 promotes proliferation and suppresses apoptosis in bladder urothelial carcinoma by upregulating Wnt3 via activating the AKT/mTOR pathway and predicts poorer survival.
Liu JY, Zeng QH, Cao PG, Xie D, Yang F, He LY, Dai YB, Li JJ, Liu XM, Zeng HL, Fan XJ, Liu L, Zhu YX, Gong L, Cheng Y, Zhou JD, Hu J, Bo H, Xu ZZ, Cao K. Liu JY, et al. Oncogene. 2018 Jul;37(29):3937-3952. doi: 10.1038/s41388-018-0223-2. Epub 2018 Apr 17. Oncogene. 2018. PMID: 29662193
PARP-1 inhibition with or without ionizing radiation confers reactive oxygen species-mediated cytotoxicity preferentially to cancer cells with mutant TP53.
Liu Q, Gheorghiu L, Drumm M, Clayman R, Eidelman A, Wszolek MF, Olumi A, Feldman A, Wang M, Marcar L, Citrin DE, Wu CL, Benes CH, Efstathiou JA, Willers H. Liu Q, et al. Oncogene. 2018 May;37(21):2793-2805. doi: 10.1038/s41388-018-0130-6. Epub 2018 Mar 7. Oncogene. 2018. PMID: 29511347 Free PMC article.
A Carcinogen-induced mouse model recapitulates the molecular alterations of human muscle invasive bladder cancer.
Fantini D, Glaser AP, Rimar KJ, Wang Y, Schipma M, Varghese N, Rademaker A, Behdad A, Yellapa A, Yu Y, Sze CC, Wang L, Zhao Z, Crawford SE, Hu D, Licht JD, Collings CK, Bartom E, Theodorescu D, Shilatifard A, Meeks JJ. Fantini D, et al. Oncogene. 2018 Apr;37(14):1911-1925. doi: 10.1038/s41388-017-0099-6. Epub 2018 Jan 25. Oncogene. 2018. PMID: 29367767 Free PMC article.
13 results