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BJU Int. 2019 Jan 18. doi: 10.1111/bju.14665. [Epub ahead of print]

External validation of a novel side-specific, multiparametric magnetic resonance imaging-based nomogram for the prediction of extracapsular extension of prostate cancer: preliminary outcomes on a series diagnosed with mpMRI targeted plus systematic saturation biopsy.

Author information

1
Department of Urology, University of Modena and Reggio Emilia, Italy.
2
Data Methods and Systems Statistical Laboratory, University of Brescia, Brescia, Italy.
3
Dept. of Radiology, University of Modena and Reggio Emilia, Italy.
4
Department of Surgical and Biomedical Sciences, Division of Radiology 2, Perugia University, Perugia, Italy.
5
Urology, Faculty of Medicine - Tanta University, Tanta.
6
Dipartimento dei Servizi Diagnostici e di Laboratorio e di Medicina Legale, Anatomia Patologica, Via del Pozzo 71, Modena.

Abstract

we read with great interest the article from Martini and Coworkers, who developed a novel side-specific, multiparametric magnetic resonance imaging (mpMRI)-based nomogram for the prediction of extracapsular extension (ECE) of prostate cancer (PCa). The knowledge of the presence of ECE would help surgeons tailor the amount of nerve-sparing and improve the tradeoff between functional and oncological outcomes of radical prostatectomy (RP)[1,2]. Several nomograms aimed to predict ECE have been developed, based on clinical and pathological variables from prostate biopsy. However, most of them are not side-specific [1] and only few tools have been externally validated. This article is protected by copyright. All rights reserved.

PMID:
30657243
DOI:
10.1111/bju.14665

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