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Neuron. 2019 Jan 16;101(2):198-200. doi: 10.1016/j.neuron.2018.12.033.

Engram Excitement.

Author information

1
Brain Mind Institute, School of Life Sciences, École Polytechnique Fédérale Lausanne (EPFL), CH-1015 Lausanne, Switzerland.
2
Brain Mind Institute, School of Life Sciences, École Polytechnique Fédérale Lausanne (EPFL), CH-1015 Lausanne, Switzerland. Electronic address: johannes.graeff@epfl.ch.

Abstract

Engram cells can encode and switch between multiple mnemonic functions, but how they intrinsically do so is unknown. Pignatelli, Ryan, and colleagues show that upon memory recall, the engram's excitability is transiently elevated, allowing its bearer to adapt to changing environments.

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