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Vasc Med. 2019 Apr;24(2):164-189. doi: 10.1177/1358863X18821816. Epub 2019 Jan 16.

First International Consensus on the diagnosis and management of fibromuscular dysplasia.

Author information

1
1 Division of Cardiovascular Medicine, University Hospitals Cleveland Medical Center and UH Harrington Heart and Vascular Institute, Cleveland, OH, USA.
2
2 Division of Cardiology, Department of Cardiovascular Diseases, Cliniques Universitaires Saint-Luc and Pole of Cardiovascular Research, Institut de Recherche Expérimentale et Clinique, Université Catholique de Louvain, Brussels, Belgium.
3
3 Department of Cardiovascular Sciences, Glenfield Hospital, Leicester, UK.
4
4 NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.
5
5 Hypertension Section, Internal Medicine Department, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
6
6 Paris Descartes University, Paris, France.
7
7 Assistance-Publique Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Hypertension Unit, Paris, France.
8
8 Institut national de la santé et de la recherche médicale, Centre d'Investigation Clinique 1418, Paris, France.
9
9 Normandie Université, UNICAEN, Inserm U1237, CHU Caen Normandie, Caen, France.
10
10 Department of Clinical and Experimental Medicine University of Pisa, Pisa, Italy.
11
11 Department of Medicine, Maastricht University Medical Center, Maastricht, The Netherlands.
12
12 Department of Cardiovascular Medicine, Cleveland Clinic Heart and Vascular Institute, Cleveland, OH, USA.
13
13 Department of Internal Medicine, Frankel Cardiovascular Center, University of Michigan, Ann Arbor, MI, USA.
14
14 University of South Carolina School of Medicine/Greenville, Greenville, SC, USA.
15
15 Association belge de patients atteints de Dysplasie Fibromusculaire/FMD Groep België (FMD-Be), Brussels, Belgium.
16
16 Department of Hypertension, Institute of Cardiology, Warsaw, Poland.
17
17 APHP, Department of Genetics and Centre for Rare Vascular Diseases, Hôpital Européen Georges Pompidou, Paris, France.
18
18 INSERM, U970 - PARCC, University Paris Descartes, Sorbonne Paris Cité, Paris, France.
19
19 Zena and Michael A Wiener Cardiovascular Institute and Marie-Josée and Henry R. Kravis Center for Cardiovascular Health; Icahn School of Medicine at Mount Sinai, New York, NY, USA.
20
20 Division of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
21
21 Fibromuscular Dysplasia Society of America (FMDSA), North Olmsted, OH, USA.
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22 Centro Fisiologia Clinica e Ipertensione, Policlinico Hospital, University of Milan, Milan, Italy.
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23 Department of Medicine, Cardiovascular Medicine Division, University of Virginia, Charlottesville, VA, USA.
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24 Department of Neurology, University of Virginia, Charlottesville, VA, USA.
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25 Department of Nephrology & Hypertension Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Brussels, Belgium.
26
26 Shanghai Institute of Hypertension and Center for Epidemiological Studies and Clinical Trials, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
27
27 Vascular Medicine Section and Vascular Center, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA.
28
28 Monash University (Central Clinical School of Medicine), Melbourne, VIC, Australia.
29
29 Department of Renal Medicine, Alfred Health, Melbourne, VIC, Australia.

Abstract

This article is a comprehensive document on the diagnosis and management of fibromuscular dysplasia (FMD), which was commissioned by the working group 'Hypertension and the Kidney' of the European Society of Hypertension (ESH) and the Society for Vascular Medicine (SVM). This document updates previous consensus documents/scientific statements on FMD published in 2014 with full harmonization of the position of European and US experts. In addition to practical consensus-based clinical recommendations, including a consensus protocol for catheter-based angiography and percutaneous angioplasty for renal FMD, the document also includes the first analysis of the European/International FMD Registry and provides updated data from the US Registry for FMD. Finally, it provides insights on ongoing research programs and proposes future research directions for understanding this multifaceted arterial disease.

KEYWORDS:

aneurysm; cervical artery dissection; fibromuscular dysplasia (FMD); percutaneous angioplasty; pressure gradients; renovascular hypertension; spontaneous coronary artery dissection

PMID:
30648921
DOI:
10.1177/1358863X18821816
[Indexed for MEDLINE]

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