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Ann Card Anaesth. 2019 Jan-Mar;22(1):47-50. doi: 10.4103/aca.ACA_66_18.

"Vitamin D" as a profile marker for cardiovascular diseases.

Author information

1
Department of Anaesthesiology, Himalayan Institute of Medical Sciences, Dehradun, Uttarakhand, India.
2
Department of Biochemistry, Himalayan Institute of Medical Sciences, Dehradun, Uttarakhand, India.
3
Department of Pediatrics, Himalayan Institute of Medical Sciences, Dehradun, Uttarakhand, India.

Abstract

Objective:

A growing body of research indicates that there exists a correlation between Vit D deficiency and cardiovascular diseases (CVD). In addition to being genetically determined, it is strongly influenced by lifestyle factors. In this study, Vit D and its interrelated factors have been studied as profile marker for identifying the risk of CVD in patients.

Methods:

The present study includes comparison of a total 200 adults CVD patients with the healthy patients as control, by measuring their serum lipid levels and Vit D concentrations with other CVD risk factors.

Results:

The average serum Vit D in CVD patients and controls are found to be 22.55±6.2 ng/ml and 37.62±3.2 ng/ml respectively, showing that 63% of CVD patients and 35% of controls are Vit D deficient. Serum lipids levels were considered as marker for patients having CVD which include high levels of total cholesterol, triglycerides, and low-density lipoprotein-cholesterol while low levels of high-density lipoproteins-cholesterol levels. Other risk factors like hypertension, lifestyle, smoking, dietary factors and nutritional status shows significantly correlation for CVD patients compared to controls.

Conclusion:

Literature supports the relationship between lipid profile and Vit D level by using this as a profile marker for CVD patients. Our study also suggests the same that vitamin D can be used as profile marker for cardiovascular diseases.

KEYWORDS:

Cardiovascular diseases; Vitamin D; hypertension; lipid profile

PMID:
30648679
DOI:
10.4103/aca.ACA_66_18
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